Effect of Turmeric Oil in Reproductive Efficiency of Immature Female Rats Exposed to Oxidative Stress Induced by Potassium Dichromate

نویسنده

  • Z. Kh. Jeber
چکیده

This study carried out to understand the effects of Potassium Dichromate (K2Cr2O7) and Turmeric Oil (TO) on reproductive efficiency. Twenty four weanling immature female albino rats aged 22 day divided randomly into 4 groups (6 rats in each group). 1 group received 0.1 ml dimethyle sulfoxide (DMSO) 5% solution as a control (I/P for 14 day), 2 group received K2Cr2O7 dissolved in distilled water (0.4 mg/kg, I/P, for 14 day), 3 group received TO dissolved in 5% DMSO solution (20 mg/kg, I/P, for 14 day), 4 group received both K2Cr2O7 +TO (0.4 mg/kg, I/P +20 mg/kg, I/P, 1⁄2 h in between, for 14 day). Rats treated with K2Cr2O7 show significant increase in Malondialdehyde (MDA) level and significant decreases in uterine and ovarian weights, serum Glutathione (GSH) level, percentage of vaginal opening time and diameter of ovarian follicles in categories (101-200), (201-300) and (>400), while those treated with TO show significant increase in uterine and ovarian weights, percentage of vaginal opening time, serum GSH, and diameter of ovarian follicles in categories (1-100) and (>400), with significant decrease in MDA level, moreover treatment with K2Cr2O7 and TO together show significant increase in uterine and ovarian weights, percentage of vaginal time opening, serum GHS level and diameter of ovarian follicles in categories (201-300) and (>400), with significant decrease in MDA level. In conclusion, K2Cr2O7 has bad effects on reproductive efficiency of female rats and TO have improvement on some of these effects. Key word: Turmeric oil, Potassium dichromate (VI), ovarian follicles, Immature rats.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of Turmeric Oil on Reproductive Efficiency of Adult Male Rats Exposed to Potassium Dichromate

This study conducted to investigate the effects of Potassium Dichromate (K2Cr2O7) and Turmeric Oil (TO) on reproductive efficiency of adult male rats. Twenty four male rats aged 100 days divided randomly into 4 groups. G1 received 1 ml of dimethyle sulfoxide (DMSO) 5% orally as control, G2 received K2Cr2O7 (24 mg/kg orally), G3 received TO dissolve in DMSO 5% (8.5 mg/kg orally) and G4 received ...

متن کامل

P-44: Effects of Nano Zinc Oxide Supplementation on Testicular Oxidative Stress in Adult Male Rats Exposed to Endurance Exercise

Background: Physical activity has a range of effects on male reproductive function depending upon the intensity and duration of the activity. Materials and Methods: In order to investigate the protective effects of nano zinc oxide on endurance exercise induced testicular oxidative stress, 30 adult male Wistar rats were randomly divided into the following groups: control group (n=10); exercised ...

متن کامل

Curcumin Pretreatment Prevents Potassium Dichromate-Induced Hepatotoxicity, Oxidative Stress, Decreased Respiratory Complex I Activity, and Membrane Permeability Transition Pore Opening

Curcumin is a polyphenol derived from turmeric with recognized antioxidant properties. Hexavalent chromium is an environmental toxic and carcinogen compound that induces oxidative stress. The objective of this study was to evaluate the potential protective effect of curcumin on the hepatic damage generated by potassium dichromate (K2Cr2O7) in rats. Animals were pretreated daily by 9-10 days wit...

متن کامل

P-28: Protective Effect of Curcumin on The Damages Induced by Nicotine on Reproductive Parameters in Male Mice

Background: Nicotine is a substance that can induce oxidative stress in the testes. And thus may reduce fertility in men. Antioxidant supplements such as curcumin can reduce oxidative stress and thus may increase fertility in men. Since the most active component responsible for the yellow color of turmeric and curcumin has anti-inflammatory and antioxidant properties. Therefore this study inves...

متن کامل

Protective Effects of Pelargonium graveolens Essential Oil on methomyl-Induced  Oxidative Stress and Spatial Working Memory Impairment in Association with Histopathological Changes in the Hippocampus of Male Wistar Rats

Introduction: Methomyl (MET) is a carbamate insecticide, used in agriculture and public health to eliminate harmful insects. Besides its advantages in agriculture, it causes neurotoxic effects. The aim of this study was to evaluate the effect of MET on Spatial Working Memory (SWM), oxidative stress parameters,  and histopathological changes in the hippocampus, as well as the possible protective...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012